Pure oud Branded perfume fragrance oil for candle and soap making wholesale diffuser essential oil new for reed burner diffusers

Acori Tatarinowii Rhizoma (ATR, Shi Chang Pu in Chinese) is the dried rhizome of Acorus tatarinowii Schott., a perennial herb of the Araceae Juss (Yan et al., 2020b). It is first recorded in the classic works of traditional Chinese medicine “Shen Nong’s Materia Medica,” and is listed as a top grade. The effects of ATR are mainly to resuscitate, calm the mind, resolve shi (dampness) and harmonize the wei (stomach) (Lam et al., 2016b). Clinically, ATR is widely used for neurological disorders, cardiovascular system, gastrointestinal digestive system, respiratory system in China (Lam et al., 2016b; Li et al., 2018a), and for the treatment of epilepsy, depression, amnesia, consciousness, anxiety, insomnia, aphasia, tinnitus, cancers, dementia, stroke, skin diseases, and other complex diseases (Lee et al., 2004; Liu et al., 2013; Lam et al., 2019; Li J. et al., 2021). In recent years, its pharmacological research has shown that ATR has a variety of pharmacological effects, including anti-epileptic, sedative, hypnotic, anti-convulsant, anti-tussive, anti-asthmatic, anti-oxidant, anti-tumor and so on (Wu et al., 2015; Lam et al., 2017a; Fu et al., 2020; Shi et al., 2020; Zhang W. et al., 2022). Previous studies indicated that ATR is promising as a potential drug candidate for the treatment of Alzheimer’s disease (AD), depression, or ulcerative colitis. In view of the exact clinical efficacy of ATR and the continuous discovery of new pharmacological activities and active ingredients, it has been widely concerned worldwide in recent years and has become one of the hot researched Chinese medicine varieties in the medical field.

The chemical composition and pharmacological effects of ATR have been extensively reported over the past few decades, and its pharmacokinetics and toxicity have also been studied in varying degrees. However, most of the previous reports are scattered, lacking systematic summary and induction of ATR. Therefore, this review aims to provide a comprehensive summary and discussion of its chemical composition, pharmacology, pharmacokinetics and toxicity characteristics, thereby contributing to the further clinical practice and application of ATR.