Pure Artemisia capillaris oil for candle and soap making wholesale diffuser essential oil new for reed burner diffusers

Liver disease, a common disorder caused by viral hepatitis, alcoholism, liver-toxic chemicals, unhealthy dietary habits and environmental pollution, is a global concern (Papay et al., 2009). However, medical treatment for this disease is often hard to administer and has a confined effect. Traditional Chinese herbal medicines, which underlie numerous prescriptions used to treat liver diseases, are still widely used by the Chinese (Zhao et al., 2014). Artemisia capillaris Thunb., Asteraceae, according to the Bencao Gangmu, the most famous records of Chinese Traditional Medicine, has been widely used as a medicine to clear heat, promote diuresis and remove jaundice and has also been used as a flavor in beverages, vegetables, and pastries because of its particular fragrance. A. capillaris has been regarded as a type of Chinese folk medicine and food by a growing number of people. Therefore, there have been considerable efforts to develop useful herbal medicines, such as A. capillaris, for the treatment of liver disease.

In recent years, herbal medicines have gained more attention and popularity for the treatment of liver disease because of their safety and efficacy (Ding et al., 2012). A. capillaris has been proven to possess good hepatoprotective activity based on modern pharmacological methods (Han et al., 2006). It is also an important medicinal material in China and is a popular anti-inflammatory (Cha et al., 2009a), choleretic (Yoon and Kim, 2011), and anti-tumor (Feng et al., 2013) herbal remedy.

Phytochemical studies have revealed a number of volatile essential oils, coumarins, and flavonol glycosides as well as a group of unidentified aglycones from A. capillaris (Komiya et al., 1976, Yamahara et al., 1989). The essential oil of A. capillaris (AEO) is one of the main pharmacological active compounds and confers anti-inflammatory (Cha et al., 2009a) and anti-apoptotic properties (Cha et al., 2009b). However, as AEO is one of the main compounds of A. capillaris, the potential hepatoprotective activities of the major constituents from A. capillaris should be explored.

In this study, the protective effect of AEO on carbon tetrachloride (CCl4)-induced hepatotoxicity was evaluated by biochemical methods, such as hepatic reduced glutathione (GSH), malondialdehyde (MDA) levels, superoxide dismutase (SOD), and glutathione peroxidase (GSH-Px) activity, as well as the activities of aspartate aminotransferase (AST) and alanine aminotransferase (ALT) in the serum. The extent of CCl4-induced liver injury was also analyzed through histopathological observations, accompanied with phytochemical analysis by GC–MS to identify the constituents of AEO.